Do not download files from unverified third-party websites that host malware. Utilize trusted gaming communities and speedrunning platforms to acquire safe files.
If Steam Cloud remains active, Steam will detect that your local file differs from the cloud and automatically overwrite your newly downloaded save with your previous progress. Binding Of Isaac Repentance 1001 Save File
You can download verified game data files directly from the resources section of the The Binding of Isaac: Repentance Speedrun Leaderboard . Do not download files from unverified third-party websites